Medicinal Chemistry of Anticancer Drugs

1. Introduction to anticancer chemotherapy 2. Antimetabolites 3. Anticancer drugs that inhibit hormone action 4. Anticancer drugs acting via radical species. Photosensitizers and photodynamic therapy of cancer. 5. DNA alkylating agents 6. Alkylating and non-alkylating compounds interacting with the DNA minor groove. 7. DNA intercalation and inhibition of topoisomerases 8. Anticancer drugs targeting tubulin and microtubules 9. Drugs targeting signaling pathways for tumour cell growth and proliferation 10.Other approaches to targeted therapy 11.Drug targeting in anticancer chemotherapy 12.Resistance to antitumour agents and drugs that modulate it 13.Cancer chemoprevention

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• Bioquímica
• Farmacologia
• Química orgânica