Adenoviral Vectors for Gene Therapy

Adenoviral Vectors for Gene Therapy

Parker, Alan L.; Curiel, David T.

Elsevier Science & Technology

04/2025

900

Dura

9780323898218

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1. Adenovirus Structure
2. Biology of Adenovirus Cell Entry: Receptors, Pathways, Mechanisms
3. Adenovirus Replication
4. Adenoviral Vector Construction I: Mammalian Systems
5. Adenoviral Vector Construction II: Bacterial Systems
6. Upstream Bioprocess for Adenovirus Vectors
7. Propagation of Adenoviral Vectors: Use of PER.C6 (TM) Cells
8. Purification of Adenovirus
9. Targeted Adenoviral Vectors I: Transductional Targeting
10. Targeted Adenoviral Vectors III: Transcriptional Targeting
11. Adenoviral Vector Targeting via Mitigation of Liver Sequestration
12. Molecular Design of Oncolytic Adenoviruses
13. Conditionally Replicative Adenoviruses-Clinical Trials
14. Innate Immune Response to Adenovirus Vector Administration In Vivo
15. Antibodies against Adenoviruses
16. Methods to Mitigate Immune Responses to Adenoviral Vectors
17. Helper-Dependent Adenoviral Vectors
18. Hybrid Adenoviral Vectors
19. Xenogenic Adenoviral Vectors
20. Engineering Chimeric Adenoviruses: Exploiting Virus Diversity for Improved Vectors, Vaccines, and Oncolytics
21. Adenoviral Vector Vaccines Antigen Transgene
22. Adenoviral Vectors Vaccine: Capsid Incorporation of Antigen
23. Utility of Adenoviral Vectors in Animal Models of Human Disease I: Cancer
24. In Situ Vaccination with Adenoviral Vectors to Treat Cancer
25. Utility of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease
26. Adenoviral Vectors for Pulmonary Disease (Pulmonary Vascular Disease)
27. Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases
28. Animal Models of Gene Therapy for Cardiovascular Disease
29. Polymer-Anchored Adenovirus as a Therapeutic Agent for Cancer Gene Therapy
30. Adenoviral Vectors for RNAi Delivery
31. Imaging and Adenoviral Gene Therapy
32. Regulation of Adenoviral Vector-Based Therapies: An FDA Perspective
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Adenovirus; gene therapy; vector; vaccine; virotherapy virus