Anti-Aging Drug Discovery on the Basis of Hallmarks of Aging

1. The aging: introduction, theories, principles and future prospective
Shabnam Shabir, Mahendra Pratap Singh
2. Brief description of aging in different levels as cellular, tissues, and organs
Anuradha Venkatakrishnan Chimata, Prajakta Deshpande, Amit Singh
3. Brief about hallmarks of aging
Josephine Esposto and Vyshnavy Balendra
4. Overview of various anti-aging strategies
Dhiraj Kumar and Faiyaz Ahmad
5. Elimination of damaged cells-dependent anti-aging strategy
Rayees Ahmad Naik, Vinodinee Dubey, Roshni Rajpoot, Debabrata Dash, Nidhi Gupta and Raj Kumar Koiri
6. Telomerase reactivation for anti-aging
TS Gopenath, Shreya Shreshtha and Kanthesh M. Basalingapa
7. Epigenetic drugs based on anti-aging approach
Tarun Minocha, Namrata Dwivedi, Chetan Panda, Anamika Misra, Barsha Baisakhi Nayak, Sanjeev Kumar Yadav, Hareram Birla and Sandeep K. Singh
8. Activation of chaperons and proteolytic system: emerging methods for anti-aging drug development
Neha Gogia, Victor Olmos, Fatema Haidery, Kimberly Luttik, Leon Tejwani, Janghoo Lim
9. Dietary restriction and mTOR and IIS inhibition: the potential to anti-aging drug approach
Sing-Hua Tsou
10. Anti-Aging Drugs, Candidates, and Food Supplements- The journey so far
Yodhaanjali JR, Rithwick Surya, Sumukha KC, Harini G, Gouri Deshpande, Chandan S,Raghu Ram Achar
11. Role of AMPK and Sirtuins as anti-aging proteins
Manjula Ramu, Sonali Vishal and Neha Gogia
12. Mitophagy and Mitohormetics: promising anti- aging strategy
Chih Li Lin
13. Clearance of senescent cells: potent anti-aging approach
Jacques Ferreira and Alex Deamer
14. Stem cell-based therapy as antiaging prospective
Sumaira Yusuf, Mahendra P. Singh
15. Anti-inflammatory therapy as a game changer towards anti-aging
Dr. Naveen Shivavedi, Anshul Shakya, Bedanta Bhattacharjee and Bhargab Deka
16. Invertebrate model organisms for aging research
Arvind Kumar Shukla, Andrew Scott and Edward Giniger

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• Endocrinologia
• Medicina geriátrica
• Farmacologia
• Metabolismo

AMPK; Age-related disorders; Aging; Aging theories; Aging-associated neurodegenerative diseases; Altered intercellular communication; Animal models; Antiaging; Antiaging approach; Antiaging compounds; Antiaging strategies; Antiaging therapies; Antiinflammatory; Apoptosis; Atrophy; Autophagy; Biological aging; Biomarkers; Calorie restriction; Candidates; Cell death; Cellular; Cellular dysregulation; Cellular reprogramming; Cellular senescence; Dietary restriction (DR); Diseases; Embryonic stem cells; Energy deprivation; Epigenetic drugs; Epigenetic modifications; Exercise; FDA; Fasting; Food supplements; Free radicals; Genomic instability; Hallmarks of aging; Homeostasis; Immunity; Impairment; Inflammaging; Inflammation; Insulin/insulin-like growth factor (IIS); Lifespan extension; Longevity; Mammalian target of Rapamycin (mTOR); Mesenchymal stem cells; Metabolism; Mitochondria; Mitochondrial dysfunction; Mitohormesis; Mitophagy; Molecular; Morphology; Natural compounds; Neurodegeneration; Neurodegenerative disorders; Oxidation; Oxidative stress; Physiology; Plasma transfusion; Protein quality control; Rapamycin; SASP; Senescence; Senolytics; Senomorphic immunomodulators; Senostatic; Sirtuins; Small molecules; Stem cell; Stem cell therapy; Stem cells; Synthetic drugs; Telomerase; Telomerase activators; Telomeres; Therapeutics; Yamanaka factors; Yoga