Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders

1. mGlu receptors in Parkinson's disease
2. Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females
3. mGlu regulation of sleep, and implications for sleep disruptions in psychiatric disorders
4. Mechanisms of mGlu receptor trafficking; alterations by methamphetamine
5. Group I mGlu and cocaine seeking
6. The role of mGlu receptors in fear and anxiety
7. Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling
8. mGlu5 as a biomarker for psychiatric disorders

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• Neurologia e neurofisiologia clínica
• Neurociências

5-HT2a; A2a; Addiction; Allosteric modulators; Alzheimer's disease (AD); Anxiety; BLA; Cognition; D2 receptor; Drug addiction; Drug discovery; Drug-seeking; Electroencephalography (EEG); Electrophysiology; Epilepsy; Estrogen; Estrogen receptor; Excitatory transmission; Female; Gene expression; Glutamate; Major depressive disorder (MDD); Membrane estrogen receptor; Memory; Metabotropic glutamate (mGlu) receptors; Metabotropic glutamate receptor; Metabotropic glutamate receptor subtype 5 (mGlu5); Metabotropic glutamate receptors; Metabotropic receptor; Methamphetamine; mGlu1; mGlu2; mGlu2 receptors; mGlu3; mGlu3 receptors; mGlu4 receptors; mGlu5; mGlu5 receptors; mGlu7; mGlu8; Motivation; mPFC; Neurology; Neurotoxicity; Nucleus accumbens; Pain; Parkinson's disease; Plasticity; Positron emission tomography (PET); Post-traumatic stress disorder (PTSD); Prelimbic cortex; Psychiatry; PTSD; Relapse; Reproduction; Resilience; Schizophrenia; Single photon emission computed tomography (SPECT); Sleep; Substance use disorder (SUD); Testosterone; Ventral hippocampus