Chemistry of Hyperpolarized Magnetic Resonance Probes

1. Hyperpolarized tracer design, synthesis and characterization
2. Optimization of hyperpolarized NMR signals in dissolution dynamic nuclear polarization
3. The chemistry of parahydrogen induced polarization (PHIP)
4. Beyond 13C-pyruvate: Biomedical applications with alternate hyperpolarized probes
5. Technical Considerations of MRI methods for validating DNP probes in small animals

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• Análise de espectro, spectrochemistry, espectrometria de massa
• Eletromagnetismo eletricidade, magnetismo e

Hyperpolarized NMR (HP-NMR); 13C and 15N labeled compounds; dynamic nuclear polarization (DNP); parahydrogen induced polarization (PHIP); relaxation; small animal imaging